Publications

Complete publication list on Google Scholar · 520 citations · h-index 13 · i10-index 14

 

 

Manuscripts in Preparation and Under Review

* denotes co-first authorship

 

1) Gerveni, A.*, Bulut, G. B.*, N. Dashti-Gibson, J. G. Trevino, J. C. Harrell, M. G. Dozmorov, and A. L. Olex. "multipletR: An Adaptive Threshold Method for Robust Multi-Species Multiplet Detection in Xenograft Single-Cell RNA-Sequencing." In preparation.

 

2) Bulut, G. B.*, I. V. A. Pereira*, F. Mirshahi, M. Seneshaw, S. Hoang, T. Andl, E. Smirnova, and A. J. Sanyal. "Alcohol and the PNPLA3-I148M Variant Interact to Reprogram Hepatic Lipid and Amino-Acid Metabolism in Obese Mice." In preparation.

 

3) Ding, B.*, Bulut, G. B.*, J. He, M. E. Logan, T. Jones, B. Krisanits, N. A. Wages, R. Yanka, D. M. Radatic, J. W. Bartges, V. J. Findlay, and D. P. Turner. "Ultra-Processed Diets and AGE Burden: Toward New Metrics of Nutritional Risk." Under review.

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4) Patel, V., Bulut, G. B., A. L. Olex, and M. G. Dozmorov. "Multiplet Detection Methods in Single-Cell Sequencing: A Review." Manuscript in preparation.

 

5) [ADD: Bulut et al ATM / adipose tissue macrophage manuscript]

 

6) [ADD: Khanna et al., hypothalamic scRNA-seq diet study: the impact of fasting and DIO on LeptinR+ cells]

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7) [ADD: Manohar et al., wrapper python package for scRNAseq annotation tools]

 

 

Selected Peer-Reviewed Publications

First-author papers marked with †

 

† Bulut, G. B., G. F. Alencar, K. M. Owsiany, A. T. Nguyen, S. Karnewar, R. M. Haskins, L. K. Waller, O. A. Cherepanova, R. A. Deaton, L. S. Shankman, S. R. Keller, and G. K. Owens. "KLF4 (Krüppel-Like Factor 4)-Dependent Perivascular Plasticity Contributes to Adipose Tissue Inflammation." Arteriosclerosis, Thrombosis, and Vascular Biology 41, no. 1 (2021): 284–301. https://doi.org/10.1161/ATVBAHA.120.314703

 

Karnewar, S., V. Karnewar, R. A. Deaton, L. S. Shankman, E. D. Benavente, C. M. Williams, X. Bradley, G. F. Alencar, G. B. Bulut, S. Kirmani, R. A. Baylis, E. R. Zunder, H. M. den Ruijter, G. Pasterkamp, and G. K. Owens. "IL-1β Inhibition Partially Negates the Beneficial Effects of Diet-Induced Atherosclerosis Regression in Mice." Arteriosclerosis, Thrombosis, and Vascular Biology 44, no. 6 (2024): 1379–92. https://doi.org/10.1161/ATVBAHA.124.320800

 

Dunaway, L. S., M. A. Luse, S. Nyshadham, G. Bulut, G. F. Alencar, N. W. Chavkin, M. Cortese-Krott, K. K. Hirschi, and B. E. Isakson. "Obesogenic Diet Disrupts Tissue-Specific Mitochondrial Gene Signatures in the Artery and Capillary Endothelium." Physiological Genomics 56, no. 2 (2024): 113–27. https://doi.org/10.1152/physiolgenomics.00109.2023

 

Zheng, S., G. B. Bulut, A. B. Kummarapurugu, J. Ma, and J. A. Voynow. "Neutrophil Elastase Degrades Histone Deacetylases and Sirtuin 1 in Primary Human Monocyte-Derived Macrophages." International Journal of Molecular Sciences 25, no. 8 (2024): 4265. https://doi.org/10.3390/ijms25084265

 

Ahmed, N. T., A. B. Kummarapurugu, S. Zheng, G. Bulut, L. Kang, A. Batheja, A. Hawkridge, and J. Voynow. "Neutrophil Elastase Targets Select Proteins on Human Blood Monocyte-Derived Macrophage Cell Surfaces." International Journal of Molecular Sciences 25, no. 23 (2024): 13038. https://doi.org/10.3390/ijms252313038

 

Deaton, R. A., G. Bulut, V. Serbulea, A. Salamon, L. S. Shankman, A. T. Nguyen, and G. K. Owens. "A New Autosomal Myh11-CreERT2 Smooth Muscle Cell Lineage Tracing and Gene Knockout Mouse Model — Brief Report." Arteriosclerosis, Thrombosis, and Vascular Biology 43, no. 2 (2023): 203–11. https://doi.org/10.1161/ATVBAHA.122.318160

 

† Bulut, G. B., R. Sulahian, H. Yao, and L. J. Huang. "Cbl Ubiquitination of p85 Is Essential for Epo-Induced EpoR Endocytosis." Blood 122, no. 24 (2013): 3964–72. https://doi.org/10.1182/blood-2013-05-506212

 

† Bulut, G. B., R. Sulahian, Y. Ma, N. W. Chi, and L. J. Huang. "Ubiquitination Regulates the Internalization, Endolysosomal Sorting, and Signaling of the Erythropoietin Receptor." Journal of Biological Chemistry 286, no. 8 (2011): 6449–57. https://doi.org/10.1074/jbc.M110.186890

 

Dutchak, P. A., S. Laxman, S. J. Estill, C. Wang, Y. Wang, Y. Wang, G. B. Bulut, J. Gao, L. J. Huang, and B. P. Tu. "Regulation of Hematopoiesis and Methionine Homeostasis by mTORC1 Inhibitor NPRL2." Cell Reports 12, no. 3 (2015): 371–79. https://doi.org/10.1016/j.celrep.2015.06.042

 

Full list of 16 peer-reviewed publications on Google Scholar.

 

 

Recent Conference Presentations

Bulut, G. B., et al. "Combinatorial Models of Biomarker Panels Reflecting Activity Versus Fibrosis Allow Identification of MASLD Sub-Phenotypes with High Precision." The Liver Meeting 2026, AASLD, Denver, CO, November 2026.

 

Pereira, I. V. A.*, Bulut, G. B.*, et al. "Metabolic and Molecular Perturbations Underlying Metabo-Inflammatory-Necrotic Activity Induced by Alcohol Exposure in the Presence of Obesity with Metabolic Dysfunction and PNPLA3-I148M Mutation." The Liver Meeting 2026, AASLD, Denver, CO, November 2026.

 

Bulut, G. B., et al. "Smooth Muscle Klf4 Promotes Spp1⁺ Macrophage Accumulation in Obese Adipose Tissue." ISMB 2026, HiTSeq Track, Washington, DC, July 2026.

 

Bulut, G. B., et al. "Alcohol Intake in the Presence of PNPLA3 Mutation Leads to Elevated Amino Acid Metabolism in Liver Injury." Keystone Symposia: Fueling MASH, April 2026.

 

Napoli, I., L. Sharma, J. Johnson, and G. B. Bulut. "Adipose Tissue Macrophage Heterogeneity in Response to Obesity." NCUR 2026, April 2026.